The development of PCR and the use
of the amplified DNA to produce unique individual profiles has brought
many exciting developments, not least in medicine (see SARS attack
and Read all about it)
and crime detection.
However there are some people who are less than happy about the
impact of PCR and other DNA technology on the society. They see
opportunities for abuse, both in terms of our health care and in
terms of crime detection.
In the UK the National DNA laboratory is the site of much research
into the use of DNA technology in the fight against crime, and it
is also the place where the national DNA database is stored. At
the moment this database holds only the DNA profiles of people who
have been involved in the criminal justice system in some way. There
is increasing pressure to have a DNA database of everyone, available
to the police and for medical emergencies such as the need for organ
or bone marrow transplants. Many people feel strongly about this
idea, whether they are for it or against it.
Here are some snippets of information about DNA. Some are scientific
fact. Some are speculation. Can you decide which are which?
Everyone talks as if DNA evidence is absolutely reliable, but it
isn’t. The DNA profiles usually prepared only use part of
our DNA. Most of the time this level of DNA fingerprinting is accurate
enough to identify an individual – but things can go wrong.
Raymond Easton suffers from Parkinson’s disease and by the
year 2000 he was so disabled that he could hardly manage to dress
himself without help. In spite of this he was charged with a burglary
which had taken place 200 miles away from his home! The error arose
because three years earlier Raymond had been involved in a family
dispute. He had been cautioned and a DNA sample was taken. By an
amazing coincidence, Raymond’s DNA matched that found at the
scene of the burglary. Fortunately DNA testing offered a way out
of the situation it had created. Once a fuller DNA analysis was
made, differences between Raymond’s DNA and that of the burglar
became clear and the charges against him were dropped.
If different types of DNA analysis are done, the chances of
there being a match range from 1 in 34 million to 1 in a billion.
Every 27 minutes, someone somewhere in the world receives an organ
transplant. But every 2 hours 24 minutes someone dies waiting for
a donor organ to turn up. When donor organs become available, it
is vitally important that they are transplanted into someone who
needs them as quickly as possible. What is more the tissue types
of the donor and recipient must match as closely as possible. DNA
profiles of donor and recipient can help to decide whether their
tissues match.
If a central DNA database held the DNA profile of everyone
(instead of being restricted to people convicted of criminal activities)
then more people would be likely to receive successful organ transplants.
What's more, organs could be used internationally far more easily.
The Human Genome Project, which has relied heavily on PCR to generate
the DNA used in the analysis, is resulting in an ever-increasing
understanding of the role of our genetics in our likelihood of developing
many different illnesses, including heart disease, cancer, sight
problems and diabetes.
There are concerns about who should have access to this sort of
information. In most cases our genes don’t predict that we
will definitely suffer from a disease, simply that we may be more
likely to get it.
If insurance companies have access to people's DNA profiles
they might refuse to give some people life insurance, or demand
huge premiums.
Since September 11th 2001 global terrorism has been seen as a real
and massive threat to peace and security.
If everyone's DNA profile was stored in an international DNA
data bank, it could make it harder for terrorists to assume false
identities and hide their origins. If terrorist attacks did occur,
it would make tracing the terrorists much easier in order to bring
them to justice.
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Different people have very different
views on the idea of a DNA data base – here
are two that you might hear :
I don’t want my DNA
on some data-base – how do I know the
police won’t fit me up for a crime I didn’t
do?
I don’t have a problem
with a DNA database. If you’ve got nothing
to hide, you’ve got nothing to fear have
you? What’s more, it might help you get
better medical treatment!
Use the material here to produce
two lists - one showing the arguments
FOR a national DNA database open to the police
in every country, the other giving arguments AGAINST
such a database.
Then write a paragraph setting
out whether or not you believe there should be
a DNA data base, explaining your reasons. |
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