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Cell division and cancer
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When cell division goes wrong
photo of kidney with tumour
Picture 10. A tumour growth on a pair of kidneys (the growth is at the top of the picture). Roll over the image to highlight the tumour.
Cell division is essential for growth, repair and reproduction. It is tightly controlled by genes inside the cell. Special genes, called oncogenes, stimulate the production of growth-stimulating chemicals that trigger cell division. If an oncogene is irreversibly switched on, it can cause uncontrolled cell division and lead to the formation of a cancer.
What is a cancer?

The uncontrolled growth of cells forms a lump called a tumour. Some tumours are benign and may not cause any problems. Others however are malignant. They can invade into other body tissues and cause severe damage. It is these malignant tumours that we call cancer.

There are over 200 different types of cancer and they can occur anywhere in the body.

Malignant tumours

When cells begin to grow in an uncontrolled way, they form a lump called a tumour. Some tumours stay within one specific area. They do not spread into surrounding tissues and may not cause any problems. If it is easy to do so, these benign tumours are usually removed by surgery. There are usually no further problems.

Cancers are dangerous types of growths called malignant tumours. In this type of tumour the cells invade the surrounding tissues. Cancer cells can break off and be carried to different parts of the body in the bloodstream. This spreads the cancer throughout the body where it can cause serious damage and eventually death.

Interacitve graphic of tumour growth
Picture 11. Growth and spread of a tumour.
The growth and spread of a malignant tumour
Roll over the words to see how a malignant tumour grows and spreads.
  • Step 1. The primary tumour develops as a group of cells that are growing out of control.

  • Step 2. The tumour gets bigger and stimulates blood vessels to supply it from the surrounding tissues.

  • Step 3. Tumour cells squeeze into blood and lymph vessels and move to other parts of the body

  • Step 4. When the tumour cells reach other areas of the body, like the liver and lungs, they begin to grow and form secondary tumours. If they are not treated quickly enough, the damage that these secondary tumours cause can be fatal.

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Question 5
Choose the best answers to fill in each of the blanks.

Our bodies are made up of small units called . Each one is controlled by a that contains the genetic code in .They are dividing all the time. Normally they are prevented from over-multiplying by the . However, sometimes they start mulitplying uncontrollably and grow into a . If they are they can spread to other parts of the body.