| Disorder: Atherosclerosis and Angina.
Facts: 1.5 million people suffer from angina in the UK.
Symptoms: During an angina attack, there are chest pains which may spread to the shoulders and both arms. Attacks are often triggered by activity and stop within minutes of the person resting. In severe cases, even everyday activities like climbing the stairs can start an attack.
Causes: Atherosclerosis is where arteries are partly blocked by fatty deposits that build up and harden on their inside wall. If this happens in a coronary artery it can cause angina or even a heart attack.
The fatty deposits increase over a period of years. They are made worse by high levels of animal fats and cholesterol in the diet, although some people are genetically more susceptible to developing atherosclerosis than others. Eating less fat, particularly saturated fat, and eating a high fibre diet can lower the total amount of cholesterol in the blood and particularly the LDL cholesterol (this is the harmful form of cholesterol). Medicines such as statins are also used to reduce cholesterol levels.
During activity the heart rate increases and muscle cells demand more oxygen. The narrowed arteries cannot supply enough blood to keep up with this demand and this triggers the pain of an angina attack which forces the person to rest.
Diagnosis: Patients will describe the history of their angina attacks. A cardiac angiogram uses a dye in the blood to allow the flow through the cardiac arteries to be observed by x-ray. An exercise tolerance test will observe the response to increased activity.
Treatments: Angina sufferers may be able to avoid the activities that trigger an attack. Nitrates such as glyceryl trinitrate, in the form of a tablet placed under the tongue during an attack help to reduce the strain on the heart and speed up recovery. Other medicines such as beta-blockers or calcium channel blockers can be used to reduce the frequency of angina attacks.
If the atherosclerosis is severe, a person may need a heart bypass operation or coronary angioplasty (see below).
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