The system which coordinates the actions of the body in response to changes in the environment using electrical signals travelling through a system of nerves
Drugs that block receptors on or in a cell and prevent an unwanted response (in people) or may prevent a desirable response causing death (in pathogens).
Medicine that acts against bacterial infections. Penicillin is an example of an antibiotic.
A group of single-celled organisms with few organelles and where the genetic material is not contained in a membrane-bound nucleus. They include bacteria and blue-green algae (cyanobacteria).
Drugs that bind to receptors on or in a cell and stimulate a response.
Medicines often need to get inside cells to have their impact. They exert their effects in many different ways.
Drugs work at the level of the cells of the body. There are several key principles of drug action:
Drugs may be taken into cells by diffusion through the membrane, facilitated diffusion, active transport or pinocytosis.
Many drugs act as agonists or antagonists. Agonists bind to receptors on or in a cell and stimulate a response. Antagonists block receptors on or in a cell and prevent an unwanted response (in people) or may prevent a desirable response causing death (in pathogens).
Medicines often affect cell membranes or get inside of cells to have an effect. Understanding some of the ways different drugs work is a useful way of clarifying transport and control mechanisms in cells.
Bacteria are prokaryotes and there are many features of prokaryotic cells that are different from our eukaryotic cells. Antibiotics are drugs that target bacteria and cure bacterial diseases. They either kill the bacteria or stop them growing – but it is important that they do not destroy the human cells as well, so many of their actions affect bacterial cells only.
Drugs affecting the nervous system
Many drugs and poisons affect the nervous system in one way or another. They may increase or depress stimulation of particular nerve pathways, or block transmission of the impulse completely. They may bind to membrane receptors or interfere with enzyme action inside or outside of the cell as in the diagram below.