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In vitro fertilisation

In vitro fertilisation is a form of infertility treatment where ova are removed from a woman and fertilised outside of the body by sperm. The resulting zygotes are allowed to develop for a few days before one or at most two embryos are returned to the uterus to implant and develop.

Biotechnology

The use of biological organisms or enzymes to create, break down or transform a material.

Radiologist

A trained medical specialist who uses radiation therapy to treat disease.

Antibiotic

Medicine that acts against bacterial infections. Penicillin is an example of an antibiotic.

Ultrasound

High frequency sound which cannot be heard by human beings

Transplant

The process of replacing a damaged or diseased organ with a healthy organ from a dead or living donor.

HIV/AIDS

Infection caused by the human immune deficiency virus (HIV). It attacks and destroys the immune system.

Dialysis

The process of cleansing the blood through a dialysis machine after the kidneys have failed

Diabetes mellitus

A disease resulting from a lack of insulin production by the pancreas or a loss of the cell response to insulin that causes a loss of control of the glucose balance of the body.

Insulin

A hormone produced by the pancreas. It allows cells in the body to take in and store glucose.

1900 - 2000: The 20th century

In 1901, the average life expectancy in the United Kingdom was 47 years. By the year 2000 it had risen to 77 years and for someone born in the UK in 2015 it is 81 years. New medicines, childhood immunisations, improved air quality and better public hygiene has contributed to this 72% increase in the life expectancy.

The twentieth century saw some major advances in healthcare. These have included the development of:

  • Insulin: Banting and Best's work to show that insulin can be used to treat diabetes.
  • Penicillin: the discovery and development of antibiotics by Fleming, Florey and Chain.
  • Modern medicines: pharmaceutical laboratories around the world are constantly producing new treatments for diseases.

Other developments

Vaccination

First described by Edward Jenner in the 18th century, vaccination programmes to prevent deaths and serious illness from diseases such as yellow fever, poliomyelitis, measles, mumps and rubella only became common in the 20th century. In 1980 the World Health Organisation announced that the deadly smallpox virus had been completely eradicated.

Medical imaging

Physicians can now call on a range of techniques to see inside the body of their patients. X-rays, discovered by Roentgen, were the first but now sophisticated computer technology allows surgeons to plan operations and radiologist to target tumours with pinpoint accuracy. Ultrasound, magnetic resonance imagery (MRI) and computer tomography (CT) scans are all part of the doctor's diagnostic armoury.

Five MRI images of a human head
(Courtesy of Genesis12)
Technology

Advances in bioengineering, computing power, materials technology and many other areas of science have led to the development of many medical devices. During heart surgery, an artificial heart and lung machine keep the patient alive. Kidney damage can quickly kill but renal dialysis can keep patients alive even though their kidneys have failed. Hearing aids and cochlea implants bring sound to the hard of hearing. Biotechnology is allowing pure drugs, such as human insulin, to be produced in large quantities.

DNA

The human genome project started the process of unlocking the secrets held within our DNA. It is leading to a much better understanding of the genetic basis for many diseases and will enable the development of new cures in the 21st Century.

The second half of the 20th century saw tremendous advances in medicine. The first heart transplant was performed by Dr Christiaan Barnard in 1967 and on July 25th 1978, Louise Brown was the first person to be born after in vitro fertilisation. Research and development of modern medicines has made a massive contribution to the improvement in health and life expectancy.

Two worlds

Sadly, it was not all good news for medicine in the 20th Century. Many diseases can be controlled and treated but this takes money. In places such as Africa, South America and Asia, the levels of healthcare are below those found in the more well off Western nations. Diseases like HIV/AIDS, cholera, tuberculosis, pneumonia and malaria remain major killers in these regions. The challenge of medicine in the 21st Century is to make high quality healthcare available to all.

Question

a) Describe and explain the trend in the rate of new medical discoveries during the 20th century.

The rate of medical advance during the 20th century was enormous, due to improvements in technology as well as new scientific discoveries.

b) Suggest some medical developments which improve the quality of health and life, rather than being life-saving.

Medical techniques concerning fertility such as contraception and IVF, give people choice, and are not life-saving techniques in the usual sense of the word.