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Cell membranemembrane
A thin, flexible sheet-like structure that acts as a lining or a boundary in an organism.
s are vital to the way cells function. In animal cells, they form the outer layer of the cell – the ultimate barrier between the inside of the cell and its surroundings. In plant cells, the cell surface membrane is inside a relatively rigid cellulosecellulose
A complex carbohydrate which makes up plant cell walls.
cell wall but the properties of the membrane still control much of what moves into and out of the cell. Most of the organellesorganelles
A distinct part of the cell, such as the nucleus, ribosome or mitochondrion, which has structure and function.
inside a eukaryoticeukaryotic
Cells that make up animals, plants, fungi and protista. They are three-dimensional, membrane-bound sacs containing cytoplasm, a nucleus and a range of membrane-bound organelles.
cell are also membrane-bound. Understanding the properties of cell membranecell membrane
The membrane which forms the boundary between the cytoplasm of a cell and the medium surrounding it and controls the movement of substances into and out of the cell.
s is key to understanding how cells work.
Our current model of the cell membranemembrane
A thin, flexible sheet-like structure that acts as a lining or a boundary in an organism.
has been built up over many years by a combination of experimental data and electron microscopy.
The unit membraneunit membrane
Bilayer of polar lipid molecules in an aqueous environment - the basis of the structure of the cell membrane.
The basic structure of the cell membranecell membrane
The membrane which forms the boundary between the cytoplasm of a cell and the medium surrounding it and controls the movement of substances into and out of the cell.
is a bilayer of phospholipidphospholipid
A lipid molecule with a hydrophilic region around the ionic phosphate group and a long hydrophobic hydrocarbon tail that forms a bilayer in aqueous solutions.
s. Phospholipid molecules have a hydrophilichydrophilic
Molecules that absorb or dissolve in water - usually polar molecules.
‘head’ region around the ionic phosphate groupphosphate group
A molecule containing phosphorus and oxygen.
and a long hydrophobichydrophobic
Insoluble in water, repel water.
hydrocarbon tail. These polar lipids form a bilayer in aqueous solutions with the hydrophilic heads pointing outwards and the hydrophobic tails forming a hydrophobic layer in the middle. This bilayer is known as a unit membrane.
The cell membranecell membrane
The membrane which forms the boundary between the cytoplasm of a cell and the medium surrounding it and controls the movement of substances into and out of the cell.
, however, is more than a simple unit membraneunit membrane
Bilayer of polar lipid molecules in an aqueous environment - the basis of the structure of the cell membrane.
. Our current model is of a fluid phospholipidphospholipid
A lipid molecule with a hydrophilic region around the ionic phosphate group and a long hydrophobic hydrocarbon tail that forms a bilayer in aqueous solutions.
bilayer with many other molecules associated with it, floating or embedded in the lipid sea. These other molecules include cholesterolcholesterol
A lipid which can be measured in the blood. High levels are linked to an increased risk of cardiovascular disease.
, glycolipidsglycolipids
Lipids that have a carbohydrate chain attached to them. The carbohydrate chain is attached to the outside of the cell and is part of the cell recognition system.
, proteins and glycoproteinsglycoproteins
Proteins that have a carbohydrate chain attached to them. The carbohydrate chain sticks out of the outside of the cell and is part of the cell recognition system.
and they all have different functions in the membrane. This is the fluid mosaic modelfluid mosaic model
Our current model of membrane structure consisting of a fluid phospholipid bilayer with many other molecules (including cholesterol, glycolipids, proteins and glycoproteins) floating or embedded in the lipid sea, all with different functions.
of membrane structure and it explains many of the properties of membranes that we can observe experimentally.
The fluid mosaic model of the cell membrane.
Many of the functions of the surface cell membranecell membrane
The membrane which forms the boundary between the cytoplasm of a cell and the medium surrounding it and controls the movement of substances into and out of the cell.
and membranes around cell organellesorganelles
A distinct part of the cell, such as the nucleus, ribosome or mitochondrion, which has structure and function.
are similar, although there are some which are specific to the outer membrane.
The pores in the nuclear membrane allow chemicals to move into the nucleus and mRNA to move out into the cytoplasm. (Image courtesy of Don W. Fawcett/Hector E. Chemes/Bernard Gilula (CC BY-NC-ND 3.0))
Use materials of your choice – anything from plasticine to plastic bottles and beyond – make a three-dimensional model of the cell membrane that can be used to explain the structure and functions of this amazing structure.